NXS Health Strategies builds and manages the operational infrastructure your covered entity needs to maintain a compliant, financially optimized 340B program.
Today's 340B environment demands more than a TPA and a compliance policy. Covered entities face mounting risks that erode program integrity and financial performance.
NXS Health Strategies operates as your outsourced 340B department — embedding our expertise into your operations, managing ongoing compliance, and aligning our compensation to the financial outcomes we deliver.
We call this Operationalized Compliance: the systematic build-out of the policies, processes, technology, and oversight infrastructure required to sustain a defensible, optimized program.
Performance-Aligned · Recurring · EmbeddedWe work exclusively with 340B-eligible covered entities. Our team brings deep program expertise across both grant-funded entities and safety-net hospital systems.
FQHCs and FQHC Look-Alikes managing clean room compliance, referral capture, and audit readiness with limited internal pharmacy and compliance staff.
Ryan White clinics, STD clinics, and public health departments navigating 340B program eligibility, compliance requirements, and financial optimization.
Disproportionate Share Hospitals maximizing contract pharmacy networks, protecting margin from manufacturer restrictions, and defending program integrity under audit.
Rural hospitals and Critical Access Hospitals that depend on 340B savings but lack the internal resources to manage program complexity and manufacturer compliance obligations.
From entry-level program assessments to ongoing managed compliance, our services are designed to meet you where you are and grow with your organization.
| Service | Purpose |
|---|---|
| 340B Integrity & Readiness Assessment | Program "stress test" — identify compliance gaps, revenue leakage, and audit exposure |
| Program Architecture & Implementation | Full clean room build — policies, procedures, oversight infrastructure |
| Contract Pharmacy Strategy | Optimize your contract pharmacy network for maximum margin under manufacturer restrictions |
| ESP / Manufacturer Compliance Build | Data submission infrastructure to maintain contract pharmacy purchasing access |
| Referral Capture Optimization | Systematic identification and capture of eligible referral prescriptions |
| Policies & Procedures Package | Audit-ready compliance documentation suite tailored to your entity type |
| 340B Financial / Margin Analysis | Detailed financial modeling of 340B program value, leakage, and opportunity |
Full-service defense of HRSA program integrity audits — documentation, response strategy, and representation coordination.
Strategic response management for manufacturer-initiated 340B audits and data disputes under ESP and contract pharmacy arrangements.
Development and implementation of HRSA-compliant corrective action plans following audit findings or self-identified program deficiencies.
Structured support for voluntary self-disclosure of 340B program deficiencies — strategy, documentation, and HRSA communication management.
Traditional consulting firms charge for time. We charge for outcomes. Here's what makes NXS Health Strategies fundamentally different.
Our CMaaS model embeds NXS as your outsourced 340B department — delivering the compliance infrastructure, operational oversight, and strategic guidance your program needs to thrive.
We don't write policies and hand them over. We build and operate the complete compliance infrastructure — processes, oversight, monitoring, and documentation — and manage it on an ongoing basis.
We work only in 340B. Our team understands the nuanced interplay of HRSA requirements, manufacturer restrictions, ESP compliance, and contract pharmacy strategy at a depth generalists can't match.
We integrate into your operations as an extension of your team — not a vendor. We attend your meetings, know your programs, and manage your compliance calendar as if we were internal staff.
Every engagement is built with HRSA audit defensibility as the primary design criterion. Our clients don't scramble when an audit notice arrives — they hand NXS the letter and focus on operations.
Our project engagements are entry points, not endpoints. We design every project to demonstrate the ongoing value of managed compliance and facilitate a seamless transition into CMaaS.
A proven path from program stress-test to ongoing managed compliance.
We stress-test your program — identifying compliance gaps, revenue leakage, and audit exposure across every compliance dimension.
We design and build the operational infrastructure required for a compliant, optimized program — clean room, policies, TPA configuration, and workflows.
We execute targeted revenue and compliance optimization initiatives — contract pharmacy strategy, referral capture, ESP compliance, and missed-claim recovery.
We transition to an ongoing managed services model — embedding NXS as your outsourced 340B department with continuous compliance oversight and program management.
We monitor, manage, and defend your program continuously — staying ahead of regulatory changes, audit risk, and manufacturer restrictions.
NXS Health Strategies was founded to solve a persistent problem in the 340B space: covered entities pay for consulting engagements that produce deliverables, not outcomes. They receive policies they can't implement, assessments they can't act on, and recommendations from consultants who aren't accountable for the results.
We built NXS to be different. Our model is built around long-term embedded partnerships, performance-based compensation, and the operational depth required to actually manage 340B complexity — not just advise on it.
Our clients don't need another consultant. They need a 340B department. That's what we provide.
We are compensated on what we deliver — not on hours worked. This creates genuine accountability that traditional consulting models cannot provide.
We don't produce frameworks. We build and operate the systems required to run a defensible program, and we stay in those systems with you.
The 340B landscape is in constant motion. We track every HRSA guidance update, manufacturer policy change, and enforcement action and translate it into action for your program.
Tell us about your entity and your current 340B program. We'll schedule a complimentary 30-minute scoping call to identify your highest-priority opportunities.
Our initial scoping call is designed to understand your program's current state, identify your top compliance risks and revenue opportunities, and determine whether a 340B Integrity Assessment or targeted project engagement makes sense for your organization.
There's no sales pitch — only a direct, expert conversation about your program and your goals.
A member of our team will reach out within one business day to schedule your complimentary 340B scoping call.